Thymine, adenine and lipoamino acid based gene delivery systems
نویسندگان
چکیده
منابع مشابه
Thymine, adenine and lipoamino acid based gene delivery systems.
A novel class of thymine, adenine and lipoamino acid based non-viral carriers for gene delivery has been developed. Their ability to bind to DNA by hydrogen bonding was confirmed by NMR diffusion, isothermal titration calorimetry and transmission electron microscopy experiments.
متن کاملThe effect of p-stacking, H-bonding, and electrostatic interactions on the ionization energies of nucleic acid bases: adenine–adenine, thymine–thymine and adenine–thymine dimersw
COVER ARTICLE Krylov et al. The effect of π-stacking, H-bonding and electrostatic interactions on the ionization energies of nucleic acid bases PERSPECTIVE Sheppard and De La Cruz A systematic review of the application of vibrational spectroscopy to the determination of the structures of NO adsorbed on single-crystal metal surfaces The effect of p-stacking, H-bonding, and electrostatic interact...
متن کاملHydration energy of Adenine, Guanine, Cytosine and Thymine : Monte Carlo simulation
The hydration of biomolecules is vitally important in molecular biology, so in this paper thesolvation energy and radial distribution function of DNA bases have been calculated by theMonte Carlo simulation.The geometries of isolated Adenine, Guanine, Cytosine, and Thyminehave been optimized using 6-31+G(d,p) basis function sets. These geometries then will be used inthe Monte Carlo calculation o...
متن کاملAb initio study & Density functional investigational of Adenine & Thymine; Comparison of primitive Gaussian and NBO calculation
We have performed quantum-chemical ab initio in various basis sets at the Hartree-Fock andB3LYP levels for Adenine and Thymine with the program GAUSSIAN98. The Dipole,Quadrupole, Octapole and Hexadecapole moments and primitive in nine basis sets for thesemolecules are presented. The most stabilized forms of these molecules are observed in 6-311++G** basis set. We have evaluated coefficient hybr...
متن کاملDNA bending by an adenine--thymine tract and its role in gene regulation.
To gain insight into the structural basis of DNA bending by adenine-thymine tracts (A-tracts) and their role in DNA recognition by gene-regulatory proteins, we have determined the crystal structure of the high-affinity DNA target of the cancer-associated human papillomavirus E2 protein. The three independent B-DNA molecules of the crystal structure determined at 2.2-A resolution are examples of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemical Communications
سال: 2010
ISSN: 1359-7345,1364-548X
DOI: 10.1039/b924371b